Table 1

ANOVA-based mean (SE) values and 95% confidence intervals for comet assays showing results for suspended cells compared with the drug-selected (LR5) and FN-adherent resistant cell lines

Shown are results for three independent experiments.

Dose (μM)Suspended cells vs. drug-selected cellsSuspended cells vs. FN-adherent cells
8226/LR58226/SUSa8226/FN8226/SUS
25
 Mean (SE)−4.49 (16.687)20.31 (9.579)29.11 (0.888)22.40 (9.458)
 95% confidence interval−37.19 to 28.221.53–39.0827.27–30.863.86–40.93
50
 Mean (SE)14.02 (8.648)33.12 (6.218)47.73 (2.141)46.27 (5.850)
 95% confidence interval−2.93 to 30.9720.93–45.3043.53–51.9334.80–57.73
100
 Mean (SE)47.32 (9.121)67.31 (4.110)72.03 (2.09)70.67 (6.175)
 95% confidence interval29.44–65.2059.25–75.3667.93–76.1258.57–82.77
  • a SUS, suspended cells.