Table 10

Dosimetry for 90Y- or 177Lu-labeled IMP-241 using the mMu-9 × m679 F(ab′)2 bsMAb

Tissue90Y-IMP-241177Lu-IMP-241
cGy/mCicGy (normalized)acGy/mCicGy (normalized)a
Tumor14,36612,578558013,721
Blood416364124305
Liver551482161394
Lungs27724294231
Kidneys171315006101500
  • a Radiation absorbed doses are normalized to 1500 cGy to the kidneys.