Table 1

Biodistribution of 111In-IMP-241

Nude mice were injected i.v. with the peptide and necropsied at the times indicated. Values are the means ± SD (n = 4).

Tissue30 min %ID/g3 h %ID/g24 h %ID/g
Tumor1.42 ± 0.360.10 ± 0.030.03 ± 0.02
(weight, g)(0.242 ± 0.245)(0.179 ± 0.053)(0.239 ± 0.046)
Liver0.20 ± 0.030.07 ± 0.010.06 ± 0.01
Spleen0.16 ± 0.030.04 ± 0.010.04 ± 0.01
Kidney4.07 ± 0.892.13 ± 0.211.72 ± 0.69
Lungs0.47 ± 0.070.06 ± 0.020.02 ± 0.006
Blood0.39 ± 0.10<0.01a<0.01a
Stomach0.17 ± 0.150.19 ± 0.250.01 ± 0.005
Sm. int0.40 ± 0.200.54 ± 0.720.02 ± 0.006
Lg. int0.09 ± 0.010.11 ± 0.030.03 ± 0.004
  • a Radioactivity concentration below threshold of detection.