Summary of TP53 mutation analysis and EGFR FISH analysis
| Case | TP53 mutation | EGFR amplification pattern | Average EGFR number | Average control number | Mode of chromosome 7 |
|---|---|---|---|---|---|
| 1 | 2.35 | 2.31 | 2 | ||
| 2 | 3.07 | 2.92 | 3 | ||
| 3 | 3.23 | 3.18 | 3 | ||
| 4 | +++a | >100 | 3.34 | 3 | |
| 5 | +++, periphery | >100 | 3.57 | 3 | |
| 6 | +++, periphery | >100 | 2.56 | 2 | |
| 7 | +++, periphery | >100 | 2.79 | 3 | |
| 8 | +++, periphery | >100 | 3.05 | 3 | |
| 9 | + | 3.07 | 3.00 | 3 | |
| 10 | + | 2.11 | 1.99 | 2 | |
| 11 | + | +, isolated | 3.22 | 3.17 | 3 |
| 12 | + | +, isolated | 3.88 | 3.84 | 4 |
| 13 | + | +, isolated | 1.95 | 1.99 | 2 |
| 14 | + | +, isolated | 4.21 | 4.12 | 4 |
a +++ = numerous cells with amplification; periphery = amplified cells more numerous at probable edge of lesion; +, isolated = rare, scattered cells with amplification.