Table 4

Somatic genetic events in ovarian tumors that are significantly associated with changes in disease stage and tumor grade

RegionAlterationStagePaGradePbP for trendc
I/II (n = 17)III/IV (n = 48)1 (n = 11)2 (n = 44)3 (n = 83)
1p32-p34.3Gain12%40%0.040
4q15.1-pterLoss41%8%0.005
5q14-q22Loss47%77%0.03240%63%73%0.0450.018
9p13-cenLoss8%22%32%0.0930.044
11q14-q22Loss0%14%22%0.0470.056
21q22-qterGain0%25%0.027
22q12-qterGain39%20%10%0.0290.005
Xcen-q13Loss15%17%45%0.0020.002
  • a Fisher’s exact test.

  • b χ2 tests.

  • c χ2 tests for trend.