Table 1

Pathology of ARR2PBi-caFGFR1 mice

Age (mo)Tissue noLine noaPINb LesionsEpithelial cell push throughCribriform structures
APDLPVP
637331333YesYes
731131332YesYes
731431332YesNo
731531332NoNo
828921444YesYes
925021334YesYes
1037021344YesYes
1037131444YesYes
1136521443YesYes
1136721332NoNo
1146621334YesYes
1243021344YesYes
1243321433YesYes
1542621443YesYes
  • a Line 21 and 31 are independent ARR2PBi-caFGFR1 transgenic lines generated through microinjections.

  • b PIN, prostatic intraepithelial neoplasia; AP, anterior prostate; DLP, dorsal lateral prostate; VP, ventral prostate.