Table 1

Effect of API on HUVEC migration

HUVECs were plated in the upper well of the Boyden chamber in 1% serum in M199, and the indicated treatments were added to the lower wells. 2dR and dR-1-P were used at 5 μm, TP at 100 ng/ml, and the API 2-thiophenylphosphonic acid was used at 10 μm.

TreatmentCells migrated (per field)
− API+ API
None16 ± 4.319 ± 6.8
2dR94 ± 1184 ± 14
dR-1-P93 ± 1616 ± 3.9a
TP88 ± 1333 ± 4.3a
  • a Indicates significant effect of API, P < 0.05.