Table 1

Summary of growth characteristics of MXT and EMT-6 tumors during and after three courses of chemotherapy^a

Tumor	Drug	Doubling time between and after courses of chemotherapy				Time to grow to 1 cm³ (days)
Tumor	Drug	d0–d7	d7–d14	d14–d21	d21–d28	Time to grow to 1 cm³ (days)
MXT	Control	2.3	4.3	/^b	/	18
	5FU	4.4	10.2	8.8	4.8	29.5
	CY	6.9	6.2	13.9	4.9	36
EMT-6	Control	5.2	4.7	/	/	20.5
	5FU	9.6	10.6	6.1	/	29.5
	CY	14.2	8.8	13.1	/	>32^c

^a Chemotherapy 100 mg/kg CY or 50 mg/kg 5FU was given i.p. once weekly on days 0, 7, and 14.
^b Not available.
^c When experiments were ceased on day 32 after tumor inoculation, the average tumor volume of CY-treated mice was <1 cm³.