Table 2

Protein families enriched in cluster 20 early paclitaxel resistance

Functional clusterNo. of genesPAccession no.Gene nameSignal log ratioa
EarlyIntermediateLate
Inflammatory response genes40.0025M17017 IL-8 2.302.232.36
U64197 Chemokine exudus 1 3.223.003.21
M60626 Formyl peptide receptor 1 1.721.771.89
S46950 Adenosine A2a receptor 1.622.362.20
  • a The signal log ratio is the average change in expression of a transcript between baseline SKOV-3 and the respective, resistant subclone. Early, SKOV-30.003TR; intermediate, SKOV-30.03TR; late, SKOV-30.3TR. The signal log ratio is reported as the log2 ratio of the average change in expression. A log2 of 1 is a fold change of 2.