Table 1

Fluid dynamic parameters in venules in both ears of TNF-α-treated Swiss/nude mice and C57B1/6 micea

Ear tumorFlank tumorControl
Within tumorAdjacent to tumorEdge earContralateral ear
Swiss/nudenmb666644
nv172021316048
Diameter (μm)20 (20–26)24 (20–29)25 (20–27)25 (22–29)23 (20–27)25 (23–28)
Centerline velocity (mm/s)1.0c (0.6–1.3)0.6 (0.5–1.0)0.6 (0.5–0.8)0.6 (0.5–1.1)0.6 (0.4–0.8)0.6 (0.4–1.3)
C57Bl/6nm777744
nv192421154641
Diameter (μm)15 (10–17)20 (19–35)22 (19–28)24 (17–25)24 (20–27)25 (20–30)
Centerline velocity (mm/s)0.3c (0.2–0.6)0.4 (0.2–0.6)0.6 (0.4–0.8)0.5 (0.4–0.6)0.6 (0.4–0.8)0.6 (0.5–1.3)
  • a Data are presented as median values and interquartile ranges in parentheses.

  • b nm, number of mice; nv, number of vessels.

  • c P < 0.05 as compared with the control group.