Table 1

Inverse association of HER-2/neu and TAP subunit expression in breast cancer

TAP1 and TAP2 IHC scores ranging from 0 to 3 as described in “Materials and Methods” of 19 HER-2/neu and 19 HER-2/neu+ lesions are shown. The results are expressed as the number of tumor lesions corresponding to the TAP1/TAP2 IHC score. Note the inverse correlation of HER-2/neu with TAP expression, which was statistically significant for TAP1 (P < 0.05, Wilcoxon test).

HER-2/neuNo. of cases analyzedNo. of tumor lesions corresponding to the TAP1/TAP2 IHC score
O123
+196/69/103/31/0
190/57/37/95/2