Table 2

Frequency of methylation based on different cutoff points and median values in clinical samples

MarkersMethylation positive % (number of methylation positive/number of total cases)Median
TumorUrine (cancer)Serum (cancer)Urine (control)Serum (control)Cutoff valuesTumorUrine (cancer)Serum (cancer)Serum (control)Urine (control)
APC 29% (5/17)38% (10/26)6% (1/18)4% (4/91)3% (1/30)4.52.892.95000
ARF 24% (4/17)31% (8/26)6% (1/18)0% (0/91)3% (1/30)000000
CDH1 59% (10/17)38% (10/26)33% (6/18)5% (5/91)7% (2/30)0.30.280.23000
GSTP1 12% (2/17)15% (4/26)6% (1/18)0% (0/91)0% (0/30)000000
MGMT 6% (1/17)8% (2/26)0% (0/18)0% (0/91)3% (1/30)000000
p16 35% (6/17)35% (9/26)22% (4/18)0% (0/91)0% (0/30)000000
RAR-82 53% (9/17)31% (8/26)6% (1/18)9% (8/91)0% (0/30)0.100000
RASSF1A 88% (15/17)65% (17/26)11% (2/18)11% (10/91)3% (1/30)0.110.99000
TIMP3 71% (12/17)46% (12/26)17% (3/18)9% (8/91)0% (0/30)11.920.02000