Table 1

Summary of pathologic features and loss of heterozygosity (LOH) levels for the 34 tumors used for LOH analysis grouped according to membership in subclasses of a larger cohort of 89 tumors

SubclassesCluster ICluster II
IA (n = 15)IB (n = 7)IIA (n = 4)IIB (n = 8)
Tumor Grade
 I20a02525
 II2702513
 III531005062
Estrogen receptor +530100100
HER2–3+60000
P53 stain +475700
Mean fractional LOHb1437614
  • a Percentage of tumors.

  • b Fraction (%) of LOH per all informative (heterozygous) loci for each tumor.