Table 2

Common loss of heterozygosity (LOH) regions in invasive breast cancers identified using single nucleotide polymorphism array analysisa

Chromosomal regionsTumors affected (n = 34)b %cChromosomal regionsTumors affected (n = 34) %
17p135610q21–2226
17q11.2–125310q25.326
17q215312q2426
11q23–245014q2126
16q23–244715q2526
14q324422q11.23–1326
10q23–24411p3124
13q14412q35–3624
17q25387q2224
1p36359q2224
9p213521q21–22.124
11p15.4321p3421
15q15324p15.321
5q14299q3421
5q21–322912q22–2321
8p21.22913q1221
13q32294p1418
1p13266q2218
3p22–24266q2618
3p122613q2218
5q11.22618q22–2318
8p22–232619q13.418
9p23–2426Xq2818
  • a Common regions of LOH among the entire tumor set determined by permutation testing for significance with P set at ≤0.05.

  • b Total number of tumors.

  • c Percentage of tumors affected determined by visual inspection of LOH patterns as displayed in Fig. 2 <$REFLINK> .