Table 4

Association of dietary factors with breast cancer risk by egfr genotypes

Quartilesegfr genotypesa
llslss
Controls (n = 58)Cases (n = 27)ORb (95% CI)Trendc PControls (n = 290)Cases (n = 132)ORb (95% CI)Trendc PControls (n = 341)Cases (n = 152)ORb (95% CI)Trendc P
Vegetables (in g/day)0.070.850.07
1–1779(15.5%)5(18.5%)1.079(27.2%)30(22.7%)1.084(24.6%)47(30.9%)1.0
178–25414(24.1%)4(14.8%)0.32(0.03–3.60)71(24.5%)37(28.0%)1.25(0.69–2.29)88(25.8%)35(23.0%)0.85(0.48–1.48)
255–37219(32.8%)7(25.9%)0.47(0.05–4.18)80(27.6%)39(29.6%)1.14(0.63–2.08)78(22.9%)39(25.7%)0.88(0.50–1.56)
≥37316(27.6%)11(40.7%)0.07(0.004–1.07)60(20.7%)26(19.7%)1.09(0.57–2.09)91(26.7%)31(20.4%)0.56(0.32–1.00)
Red meat (in g/day)0.030.950.02
Missing1(0.02%)8(2.76%)3(2.27%)14(4.11%)3(1.97%)
1–2124(41.4%)6(22.2%)1.088(30.3%)39(29.5%)1.0109(32.0)47(30.9%)1.0
22–399(15.5%)3(11.1%)1.20(0.12–12.40)73(25.2%)33(25%)1.10(0.61–1.96)105(30.8)29(19.1%)0.71(0.41–1.23)
40–6414(24.1%)4(14.8%)1.30(0.16–10.58)72(24.8%)30(22.7%)0.97(0.54–1.74)61(17.9%)32(21.1%)1.39(0.78–2.50)
≥6510(17.3%)14(51.9%)10.68(1.57–72.58)49(16.9%)27(20.5%)1.07(0.57–2.05)52(15.2%)41(26.9%)1.86 (1.06–3.27)
  • a Genotype according to a short (≤18 CA repeats) and a long (≥19 CA repeats) allele: ss (short/short); sl (short/long); ll (long/long).

  • b Adjusted for number of full-term pregnancies (0, 1–2, ≥3), age at menarche (≤12 or ≥13 years), duration of breastfeeding (continuous), menopausal status, and family history, alcohol consumption (0, ≤18, or ≥19 g/day). OR, odds ratio; CI, confidence interval.

  • c P for test of trend of the odds ratios for the quartiles of consumption scored as ordinal variables 1 to 4.