Table 1

Clinicopathological and hypermethylation detection data of 50 ovarian cancer patients

No.AgeCell TypeGradeStageCytologyRASSF1A T/PF/SBRCA1 T/PF/SOther gene T/PF/SCA-125
154ps LMPBIAU/U/UU/U/UM/U/M p14NA
264ps LMPBIAM/U/UU/U/U4
358muc LMPBIAM/U/UU/U/U16
444ps LMPBIANDM/-/UU/-/UNA
529muc LMPBIANDU/-/UU/-/UM/-/M p162
645mix LMPBIAM/U/MU/U/UNA
767muc LMPBIAU/U/UM/U/M54
836muc LMPBIAU/U/UU/U/UM/U/U APC102
928ps LMPBIIIB+U/U/UU/U/UM/M/M p16NA
1042ps LMPBIBM/U/MU/U/U216
1156endoIIANDM/-/MM/-/M302
1271endoIIIAM/M/MU/U/U1696
1318mucIIIAM/U/MU/U/U44
1468endoIIIAU/U/UM/U/M5
1567ccIIIIAM/U/MU/U/U25
1657ccIIIIAM/U/MU/U/U77
1738endoIIIC+M/M/MM/M/M548
1862undiffIIIIC+U/U/UU/U/UM/M/M APCNA
1954psIIIIII+U/U/UM/M/M2000
2069psIIIIIIB+U/U/UU/U/UM/M/M APC96
2178psIIIIIICNDM/-/UM/-/U4739
2260psIIIICM/M/MU/U/U129
2364psIIIIIICNDU/-/UM/-/U2849
2434mucIIIICNDM/-/MU/-/UNA
2553psIIIIIICNDM/-/MU/-/U277
2681psIIIIIIC+U/U/UM/M/U8796
2775mucIIIIIIC+U/U/UM/M/MNA
2857psIIIIIIC+U/U/UU/U/UM/U/M DAPKNA
2953psIIIIIIC+U/U/UU/U/UM/M/M p16693
3067psIIIIIIC+U/U/UU/U/UM/M/M DAPK207
3156ps & ccIIIIIIC+U/U/UU/U/UM/M/M p14500
3267ps & endoIIIIIIC+M/M/MU/U/U1785
3339psIIIIICatypicalU/U/UM/M/M272.5
3471psIIIIIIC+U/U/UM/M/M80.5
3568ccIIIIIIC+M/M/MU/U/UNA
3650psNAIIICatypicalU/U/UU/U/UM/M/M p16NA
3750endo & ccIIIIIICU/U/UU/U/UM/U/M p1436
3841psIIIIIC+M/M/MU/U/U11
3969psIIIIIIC+U/U/UU/U/UM/M/U APC96
4062psIIIV+U/U/UM/M/M473
4176psIIIIV+M/M/MU/U/U732.9
4272tcIIIIV+U/U/UU/U/UM/M/M APCNA
4371ccIIIIVNDM/-/MU/-/UNA
4462psIIIIV+M/M/MU/U/U498
4549psIIIV+U/U/UU/U/UM/M/M p16289
4675ps ppIIIIII+U/U/UU/U/UM/M/M DAPK153
4769ps ppIIIIIIC+M/M/MU/U/UNA
4885ps ppIIIIIIC+M/M/MU/U/U413
4978ps ppIIIIIIC+M/M/MU/U/U617
5087ps ppIIIIV+M/M/MU/U/U1206
  • NOTE. Age (years); n, no; y, yes; cell type; ps, papillary serous; muc, mucinous; cc, clear cell; endo, endometroid; tc, transitional cell; undiff, undifferentiated; pp, primary peritoneal origin; LMP, low malignant potential; grade = American Joint Committee on Cancer; stage = American Joint Committee on Cancer stage grouping; M, methylated; U, unmethylated; other gene, only the gene methylated in the tumor and used as a target for detection in the matched serum and peritoneal fluid is listed. A CA-125 value > 35 is considered abnormal and 0 to 35 as the normal range. Patient 9’s LMP tumor had noninvasive implants outside the ovary and was therefore considered a stage III lesion; NA, not available; ND, not determined.