Table 1

Association of reported history of allergy, infection, and autoimmune disease on the occurrence of primary brain tumors in four studies

Study typeImmune factorDiagnosisRisk ratio (95% CI)Reference
Case/controlAllergyGlioma0.5 (0.3–0.7)Wiemels et al. (2)
Case/controlAllergyGlioma0.6 (0.5–0.7)Schlehofer et al. (3)
Meningioma0.9 (0.7–1.2)
Case/controlInfectionsGlioma0.7 (0.6–0.9)Schlehofer et al. (3)
Meningioma0.7 (0.5–1)
Case/controlAllergyGlioma0.7 (0.5–0.9)Brenner et al. (5)
Case/controlAutoimmune diseaseGlioma0.5 (0.4–0.7)Brenner et al. (5)
Case/controlAutoimmune diseaseMeningioma0.6 (0.4–0.9)Brenner et al. (5)
Retrospective cohortAllergyGlioma0.5 (0.2–1.1)Schwartzbaum et al. (4)