Table 1

Effect of azoxymethane on tumor formation in wild-type and BubR1+/− mice

Experimental groupMicroadenomas (<1.5 mm)aAdenomasbAdenocarcinomas
BubR1+/+ mice0.4 ± 0.2c0 ± 00 ± 0
BubR1+/− mice7.2 ± 1.12.6 ± 0.71.2 ± 0.4
  • a Direct microscopic observation.

  • b Histological evaluation.

  • c Mean ± SE (N = 10).