Table 2

Demonstration of the immunophenotype of hormone-refractory metastatic (met) prostate cancers in 30 rapid autopsy cases

IDNo. of met sitesARAMACRSYNMIB-1CGAPSAMorphologyTime from chemotherapy to death (months)
153.6 ± 2.817.7 ± 2.30.7 ± 0.15 ± 0.61.8 ± 3.879.6 ± 8.7GP 5 + 4+NE26
224.2 ± 2.57.5 ± 1.00.6 ± 3.38.4 ± 0.43.9 ± 1.624.1 ± 4.6NE21
3844.3 ± 10.87.7 ± 2.10.2 ± 1.94.8 ± 0.91.5 ± 0.862.7 ± 14.4GP4 + 320
4223 ± 4.12.5 ± 0.30.8 ± 1.01.6 ± 0.30.8 ± 0.528.1 ± 5.0GP 513
5521.8 ± 210.7 ± 0.70.3 ± 1.53.3 ± 0.33 ± 0.416.5 ± 2.8GP 57
6314.1 ± 3.730.8 ± 2.93.8 ± 1.01.3 ± 0.33.9 ± 0.649 ± 6.3GP 5 + 42
72NA1.9 ± 0.320.7 ± 2.22.8 ± 0.38.4 ± 0.773.8 ± 1.7GP 434
838.3 ± 0.037.7 ± 3.71.4 ± 0.07.4 ± 0.213.9 ± 0.238 ± 6.1GP 5 + 416
9120 ± 1.230.4 ± 2.512 ± 0.63.4 ± 0.15.1 ± 0.166.6 ± 1.7GP 4 + 321
10316.9 ± 2.615.6 ± 2.219.9 ± 1.16.5 ± 0.710 ± 0.431.1 ± 4.0GP 5 + 412
111NA11.4 ± 0.57 ± 014.3 ± 1.92.4 ± 0.13.3 ± 0.1Undifferentiated5
1230.3 ± 0.22.4 ± 0.20.4 ± 0.12.1 ± 0.31.1 ± 0.161.9 ± 0.2GP 5 + 419
134NA0.6 ± 0.10.4 ± 0.25.2 ± 1.22 ± 0.549.8 ± 2.8GP 5 + 4+NE13
1460.7 ± 2.723.9 ± 4.90.7 ± 2.12 ± 0.61.2 ± 1.383.5 ± 10.1GP 5 + 417
15256.3 ± 2.817.2 ± 40.4 ± 0.21.7 ± 0.70.7 ± 0.398.1 ± 2.8GP 5 + 45
16485.6 ± 4.716 ± 2.50.7 ± 0.214.8 ± 1.31.5 ± 0.296.9 ± 2.2GP 514
1740.4 ± 0.25.7 ± 2.48.1 ± 2.44.9 ± 0.54.1 ± 1.22 ± 2.7GP 5 + 4+311
18275 ± 5.43.8 ± 0.20.2 ± 0.015.1 ± 0.21.7 ± 1.058.7 ± 1.7GP 414
19343 ± 74.1 ± 2.72.3 ± 1.04.2 ± 0.40.9 ± 0.787.1 ± 2.0GP 528
20423.9 ± 50.4 ± 0.10.4 ± 1.52.3 ± 0.28.8 ± 1.22.1 ± 2.6GP 5 + 414
2130.2 ± 1.33.1 ± 0.30.9 ± 0.91.8 ± 0.31.9 ± 0.651.2 ± 4.4GP 5 + 430
2240.3 ± 1.33.6 ± 0.91.6 ± 4.58.8 ± 1.65.5 ± 1.64.1 ± 2.8Small cell9
23352.4 ± 0.422.7 ± 3.97.8 ± 1.63.2 ± 1.05 ± 1.158.1 ± 5.1GP 5 + 445
2464.4 ± 3.68.2 ± 1.23.4 ± 3.47.5 ± 2.018 ± 4.610 ± 10.0Small cell9
25232.9 ± 4.210.5 ± 0.61.2 ± 0.311.9 ± 0.11.5 ± 0.13.3 ± 6.3GP 5 + 40
26521.7 ± 1.915.6 ± 4.71.8 ± 1.97.8 ± 1.93.6 ± 0.719.9 ± 5.3GP 5 + 435
27129.2 ± 3.78 ± 0.36.9 ± 0.62.3 ± 0.17.3 ± 0.940.6 ± 2.1GP 5 + 415
28483.4 ± 8.316.7 ± 4.30.2 ± 1.65.9 ± 1.01.1 ± 0.864.5 ± 6.5GP 5 + 461
29147.3 ± 0.013.3 ± 015.3 ± 1.64.8 ± 0.36.8 ± 0.033.4 ± 2.5GP 5 + 48
30787 ± 7.75.8 ± 2.70.5 ± 1.94.6 ± 1.01.9 ± 0.98.5 ± 5.8GP 5 + 416
  • NOTE. Median % staining (± SEM) of all metastatic samples from 30 rapid autopsy cases evaluated with different immunomarkers.

  • Abbreviations: ID, identification number; GP, Gleason pattern; NE, neuroendocrine; NA, Not available.