Table 3

Parameters associated with prostate-specific antigen recurrence after radical prostatectomy for clinically localized prostate cancera

PRelative risk95% confidence interval
Upper boundLower bound
Univariate analysis
 Gleason score0.091.90.94
 Preoperative prostate-specific antigen (PSA)0.031.111.1
 Tumor dimension0.041.913.4
 Extraprostatic extension<0.0000131.75.2
 Seminal vesicle invasion0.0017.42.225.1
 Positive surgical margins<0.000013.82.16.9
 Tumor stage (American Joint Committee on Cancer, T3 versus T2)0.0012.71.54.7
 Metastasis-associated protein 1 (MTA1) negative0.022.81.26.7
Multivariable analysis
 Preoperative PSA0.0141.111.1
 Extraprostatic extension0.0062.11.23.7
 Positive surgical margins<0.000014.128.1
 MTA1 negative0.0053.81.59.6
  • a Gleason scores (GS) were divided into three categories: GS ≤ 6, GS = 7, and GS ≥ 8. Tumor stage: progression from AJCC tumor stage T2 to AJCC tumor stage T3. MTA1: negative staining defined as weak and absent staining.