Table 2

Least-squares mean percentage breast density by ARa genotype

CharacteristicAR GenotypePPtrend
S/SS/LL/LL/L vs S/S
All
n74185145
 %densityb34.833.035.60.790.500.64
Caucasians
n2497125
 %densityc36.233.635.30.840.780.86
African-Americans
n508820
 %densityc35.433.939.80.400.480.62
Premenopausal
n359066
 %densityb39.336.841.10.710.440.55
Postmenopausal
n348576
 %densityb34.033.034.20.950.920.89
Ever HT
n226552
 %densityb31.433.537.30.290.500.25
Never HT
n122024
 %densityb38.233.626.00.110.270.11
ET users
n122725
 %densityb34.531.632.80.830.920.86
EPT users
n103827
 %densityb25.735.741.40.040.110.04
Current EPT userd
n93222
 %densityb24.637.941.80.030.100.05
  • a AR, androgen receptor; EPT, estrogen progestin therapy; ET, estrogen therapy.

  • b Adjusted for race: African-American, Caucasian; age at mammogram (years): 35–39, 40–44, 45–49, 50–54, 55–59, 60–64; body mass index (kg/m2): <22, 22–24.9, 25–29.9, ≥30.

  • c Adjusted for age at mammogram and body mass index.

  • d Current EPT=used EPT within 1 year before mammogram.