Table 2

Characteristics of BCL2-IGH translocation in peripheral blood lymphocytes of farmers occupationally exposed to pesticides according to pesticide use period

OverallSampling period
Low pesticide use period (n = 32)High pesticide use period (n = 21)Pa
Median time since last exposure (in days)285530.0005
BCL2-IGH prevalenceb71%65%81%0.10
BCL2-IGH frequency (mean +/− SD)c4.5 × 10 ± 9.3 × 102.89 × 10 ± 4.1 × 106.94 × 10 ± 13.7 × 100.12
BCL2-IGH frequency for positives farmers onlyc (mean +/− SD)6.1 × 10 ± 1.06 × 104.2 × 10 ± 4.6 × 108.5 × 10 ± 14.9 × 100.10
Oligoclonalityd52.8% (17/36)42.8% (9/21)53.3% (8/15)0.74
  • a P between the two sampling periods.

  • b Number of individuals with at least one positive specific PCR product.

  • c Results are expressed as the number of BCL2-IGH bearing cells in 106 normal cells measured with the Poisson’s assumptions.

  • d Represents the number of individuals with multiple BCL2-IGH rearrangements on the number of analyzed positive individuals, as shown by DNA sequencing of junction sequences.