Table 1

Proteins identified as associated with histological grading of gliomas

Accession no.Entry nameDescriptionFunctionpIMass (kDa)PPositive rate (n)
High gradeLow grade
High-grade glioma-associated proteins
UnknownUnknown7.4588.60.035421/650/10
P15311EZRI_HUMANEzrin (p81; cytovillin)Cytoskeleton/signal transduction6.0486.10.006438/651/10
P05129KPCG_HUMANProtein kinase C γSignal transduction8.179.50.012238/652/10
P11021GR78_HUMAN78-kDa glucose-regulated protein (GRP78)Molecular chaperone4.9975.70.006148/652/10
Q9BZE4NOG1_HUMANNucleolar GTP-binding proteinGTP-binding protein5.0474.10.028325/650/10
UnknownUnknown8.0369.50.000149/651/10
UnknownUnknown7.8768.60.001832/650/10
P05121PAI1_HUMANPlasminogen activator inhibitor-1Protease6.9648.30.033744/653/10
P04765IF41_HUMANEukaryotic initiation factor 4A (p37)Translation regulation4.9546.10.000140/650/10
UnknownUnknown4.7145.90.016245/653/10
UnknownUnknown4.5645.20.000156/653/10
Q02750MPK1_HUMANMAPKa/ERK kinase 1Signal transduction6.7643.30.023334/651/10
UnknownUnknown4.4241.30.007154/654/10
P07355ANX2_HUMANAnnexin II (lipocortin II)Phospholipid-binding protein7.1238.50.00650/653/10
P16220CREB_HUMANcAMP-response element binding protein-1Transcription regulation6.236.60.003252/653/10
P09525ANX4_HUMANAnnexin IV (lipocortin IV)Phospholipid-binding protein5.635.80.032826/650/10
P07339CATD_HUMANCathepsin DProtease/apoptosis induction5.6334.10.044338/652/10
P35232PHB_HUMANProhibitinMolecular chaperone5.7429.80.001748/652/10
P18669PGM1_HUMANPhosphoglycerate mutase 1Metabolic enzyme6.6728.60.000160/654/10
P09488GTM1_HUMANGlutathione S-transferase MMetabolic enzyme7.3525.60.002557/654/10
P20336RB3A_HUMANRAB3A, member RAS oncogene familyGTP-binding protein8.3124.90.047446/653/10
P11233PALA_HUMANRas-related protein Ral-AGTP-binding protein7.0523.60.035249/654/10
P04792HS27_HUMANHeat shock 27-kDa protein (HSP27)Molecular chaperone5.6122.80.001937/650/10
P06749RHOA_HUMANTransforming protein Rho AGTP-binding protein6.3521.80.002458/654/10
P15154RAC1_HUMANRac1GTP-binding protein8.121.50.000155/652/10
UnknownUnknown8.0620.30.000251/652/10
UnknownUnknown8.1619.40.045327/650/10
Low-grade glioma-associated proteins
UnknownUnknown6.582.10.000928/6510/10
UnknownUnknown8.0667.60.024626/658/10
P00367DHE3_HUMANGlutamate dehydrogenase 1Metabolic enzyme7.2661.30.006327/659/10
P30101PDA3_HUMANProtein disulfide isomerase A3Molecular chaperone4.7656.80.001521/659/10
P06733ENOA_HUMANPhosphopyruvate hydrataseMetabolic enzyme7.01470.000116/656/10
UnknownUnknown8.0439.8<0.000115/6510/10
UnknownUnknown7.0639.2<0.000119/6510/10
P09211GTP_HUMANGlutathione S-transferase PMetabolic enzyme5.4323.30.002122/659/10
P02511CRAB_HUMANα Crystallin B chainCytoskeleton/molecular chaperone6.8420.20.000123/6510/10
P38936CDN1_HUMANCyclin-dependent kinase inhibitor 1 (p21)Cell cycle regulation7.9219.70.036920/658/10
  • a MAPK, mitogen-activated protein kinase; ERK, extracellular signal-regulated kinase.