Table 1.

Enzasturin (LY317615.HCl) structure and PKC inhibition (IC50, μmol/L)

Embedded Image
PKCβPKCαPKCγPKCε
0.0060.0390.0830.110
  • NOTE: IC50 values were calculated from a 10-point curve from filter-binding assays run at 30 μmol/L ATP.