Table 5.

Mortality follow-up (1956-1999) among DDT-exposed workers: relative risks by quartile of cumulative and average exposure

A. Cumulative exposure quartiles
Unexposed (Pyr: 40,172.96)0.01-21.6 mg (Pyr: 27,787.44)21.7-531.4 mg (Pyr: 27,313.08)531.5-2,755 mg (Pyr: 28,017.29)≥2,755.1 mg (Pyr: 27,366.03)χ2 test for trend (P)
nRR (95% CI)nRR (95% CI)nRR (95% CI)nRR (95% CI)nRR (95% CI)
All deaths8881.0 (—)5101.0 (0.9-1.1)5441.0 (0.9-1.1)5500.9 (0.8-1.0)5450.8 (0.7-0.9)13.07 (<0.001)
All cancers2281.0 (—)1541.1 (0.9-1.4)1330.9 (0.7-1.1)1340.9 (0.7-1.1)1521.0 (0.8-1.2)1.38 (NS)
Stomach cancer111.0 (—)81.2 (0.5-3.0)81.1 (0.5-2.8)131.7 (0.7-3.7)162.0 (0.9-4.4)3.72 (0.05 > P< 0.10)
Liver cancer211.0 (—)131.0 (0.5-2.1)161.2 (0.6-2.4)80.5 (0.2-1.2)141.0 (0.5-1.9)0.50 (NS)
Pancreas cancer91.0 (—)61.1 (0.4-3.1)81.4 (0.5-3.6)50.8 (0.3-2.5)30.5 (0.1-1.8)0.87 (NS)
Lung cancer681.0 (—)551.3 (0.9-1.8)320.7 (0.5-1.1)290.6 (0.4-1.0)340.7 (0.5-1.1)6.73 (<0.01)
Prostate cancer161.0 (—)60.6 (0.3-1.7)80.8 (0.3-1.9)70.6 (0.3-1.5)100.9 (0.4-1.9)0.27 (NS)
Bladder cancer111.0 (—)50.8 0.3-2.360.9 (0.3-2.3)111.4 (0.6-3.3)121.5 (0.7-3.4)1.67 (NS)
Leukemia81.0 (—)51.1 (0.4-3.5)30.7 (0.2-2.8)61.3 (0.5-3.9)40.8 (0.2-2.9)0.03 (NS)
B. Average exposure quartiles
Unexposed (Pyr: 41,072.96)0.001-0.061 mg (Pyr: 28,145.26)0.062-6.533 mg (Pyr: 31,361.09)6.534-9.868 mg (Pyr: 24,106.32)≥9.869 mg (Pyr: 26,871.16)χ2 test for trend (P)
nRR (95% CI)nRR (95% CI)nRR (95% CI)nRR (95% CI)nRR (95% CI)
All deaths8881.0 (—)5211.0 (0.9-1.1)5870.9 (0.8-1.0)4800.9 (0.8-1.0)5610.9 (0.8-1.0)9.69 (<0.005)
All cancers2281.0 (—)1601.1 (0.9-1.4)1510.9 (0.7-1.1)1261.0 (0.8-1.2)1360.9 (0.7-1.1)2.89 (NS)
Stomach cancer111.0 (—)81.2 (0.5-3.0)111.4 (0.6-3.2)142.1 (0.9-4.6)121.5 (0.7-3.4)2.09 (NS)
Liver cancer211.0 (—)151.2 (0.6-2.3)120.8 (0.4-1.6)70.5 (0.2-1.3)171.2 (0.6-2.2)0.09 (NS)
Pancreas cancer91.0 (—)50.9 (0.3-2.7)81.2 (0.5-3.2)40.8 (0.2-2.6)50.8 (0.3-2.5)0.10 (NS)
Lung cancer681.0 (—)501.1 (0.8-1.7)410.8 (0.6-1.2)280.7 (0.5-1.1)310.7 (0.4-1.1)5.70 (<0.05)
Prostate cancer161.0 (—)60.6 (0.2-1.6)90.8 (0.4-1.8)91.0 (0.4-2.2)70.6 (0.2-1.5)0.61 (NS)
Bladder cancer111.0 (—)60.9 (0.3-2.5)81.0 (0.4-2.5)111.6 (0.7-3.8)91.1 (0.5-2.7)0.52 (NS)
Leukemia81.0 (—)51.2 (0.4-3.6)61.3 (0.4-3.7)30.8 (0.2-2.9)40.8 (0.2-2.9)0.15 (NS)
  • NOTE: As in Tables 3 and 4, risks are adjusted by age, age at first exposure, and ethnic origin.