Table 1.

Development of papilloma, dysplasia, and invasive carcinoma in the rat esophagus

GroupTreatmentNo. ratsLesion incidence (%)
PapillomaDysplasiaCarcinoma
AAMN, 4 wk633330
BAMN, 4 wk → TPA, 8 wk6335017
CAMN, 12 wk → TPA, 4 wk6673383
DNo treatment, control6000