Table 1.

Characteristics of TLR4 SNPs

IIPGA name	SNP name	Nucleotide change	Location	rs no.	Minor allele frequency, (controls)	HWE P (controls)
TLR4_851	SNP1	A→G	5′ UTR	rs2770150	26.3	0.32
TLR4_1859	SNP2	G→A	5′ UTR	rs11536858	38.5	0.25
TLR4_1893	SNP3	A→G	5′ UTR	rs6478317	35.3	0.18
TLR4_2032	SNP4	T→C	5′ UTR	rs10116253	28.5	0.29
TLR4_2437	SNP5	A→G	5′ UTR	rs1927914	35.1	0.15
TLR4_2856	SNP6	T→C	5′ UTR	rs10759932	16.2	0.10
TLR4_7764	SNP7	G→A	Intron	rs1927911	29.0	0.44
TLR4_9263	SNP8	C→A	Intron	rs11536878	12.3	0.0001
TLR4_11547	SNP9	A→G	Intron	rs5030717	12.8	0.09
TLR4_11912	SNP10	G→T	Intron	rs2149356	34.1	0.02
TLR4_13015*	SNP11	A→G	Exon	rs4986790	5.2	0.02
TLR4_15844*	SNP12	G→C	3′ UTR	rs11536889	13.8	0.53
TLR4_16649	SNP13	G→C	3′ UTR	rs7873784	17.9	0.02
TLR4_17050	SNP14	T→C	3′ UTR	rs11536891	18.0	0.06
TLR4_17723	SNP15	G→A	3′ UTR	rs11536897	5.4	0.03
TLR4_17923	SNP16	C→A	3′ UTR	rs1536898	14.8	0.26

NOTE: TLR4_13015 (SNP11) corresponds to the nonsynonymous SNP, 8552A/G, in the report of Zheng et al. (14). This nonsynonymous amino acid substitution, D299G, is in strong linkage disequilibrium with the nonsynonymous change, T399I, which was not selected in this study. TLR4_15844 (SNP12) corresponds to the prostate cancer risk SNP, 11381 G/C, in the report of Zheng et al. (14).