Effect modification by age
SNP | Noncarriers | Carriers | P* | ||
---|---|---|---|---|---|
Case/control | OR | Case/control | OR (95% CI) | ||
SNP1 | |||||
Age ≤65 | 132/171 | 1.00 | 169/139 | 1.47 (1.09-2.00) | 0.22 |
Age >65 | 187/203 | 1.00 | 185/167 | 1.20 (0.91-1.58) | |
SNP2 | |||||
Age ≤65 | 127/121 | 1.00 | 184/194 | 0.92 (0.68-1.24) | 0.48 |
Age >65 | 146/149 | 1.00 | 239/231 | 1.04 (0.79-1.37) | |
SNP3 | |||||
Age ≤65 | 146/132 | 1.00 | 163/180 | 0.84 (0.63-1.14) | 0.27 |
Age >65 | 162/163 | 1.00 | 218/210 | 1.04 (0.79-1.37) | |
SNP4 | |||||
Age ≤65 | 193/157 | 1.00 | 118/157 | 0.64 (0.47-0.86) | 0.01 |
Age >65 | 200/203 | 1.00 | 184/177 | 1.02 (0.78-1.35) | |
SNP5 | |||||
Age ≤65 | 146/132 | 1.00 | 151/173 | 0.79 (0.59-1.07) | 0.18 |
Age >65 | 151/158 | 1.00 | 210/206 | 1.00 (0.76-1.31) | |
SNP6 | |||||
Age ≤65 | 227/210 | 1.00 | 73/100 | 0.67 (0.47-0.94) | 0.53 |
Age >65 | 284/262 | 1.00 | 93/109 | 0.79 (0.57-1.09) | |
SNP7 | |||||
Age ≤65 | 190/152 | 1.00 | 120/161 | 0.63 (0.46-0.85) | 0.01 |
Age >65 | 198/200 | 1.00 | 186/176 | 1.05 (0.80-1.39) | |
SNP9 | |||||
Age ≤65 | 250/230 | 1.00 | 51/79 | 0.59 (0.40-0.87) | 0.41 |
Age >65 | 299/281 | 1.00 | 70/89 | 0.72 (0.51-1.03) | |
SNP10 | |||||
Age ≤65 | 153/138 | 1.00 | 144/170 | 0.76 (0.56-1.02) | 0.17 |
Age >65 | 167/167 | 1.00 | 203/196 | 1.03 (0.78-1.35) | |
SNP11 | |||||
Age ≤65 | 258/281 | 1.00 | 37/24 | 1.61 (0.94-2.74) | 0.04 |
Age >65 | 330/324 | 1.00 | 32/40 | 0.78 (0.48-1.27) | |
SNP12 | |||||
Age ≤65 | 236/233 | 1.00 | 73/80 | 0.91 (0.63-1.29) | 0.40 |
Age ≤65 | 279/280 | 1.00 | 104/94 | 1.12 (0.81-1.54) | |
SNP13 | |||||
Age ≤65 | 222/205 | 1.00 | 73/101 | 0.66 (0.47-0.94) | 0.03 |
Age >65 | 253/254 | 1.00 | 121/109 | 1.13 (0.83-1.53) | |
SNP14 | |||||
Age ≤65 | 227/208 | 1.00 | 73/101 | 0.66 (0.46-0.93) | 0.06 |
Age >65 | 253/258 | 1.00 | 116/114 | 1.00 (0.73-1.35) | |
SNP15 | |||||
Age ≤65 | 278/273 | 1.00 | 21/34 | 0.60 (0.34-1.06) | 0.09 |
Age >65 | 318/333 | 1.00 | 37/33 | 1.12 (0.69-1.82) | |
SNP16 | |||||
Age ≤65 | 232/211 | 1.00 | 56/86 | 0.59 (0.41-0.86) | 0.02 |
Age >65 | 255/267 | 1.00 | 95/90 | 1.05 (0.76-1.45) |
↵* P is testing the significance of the interaction.