Table 2.

Summary of avidity and isotype of anti-HER2 antibodies

Immunoglobulin levels (μg/mL)% Avidity
HER2 lgGlgG1lgG2lgG3lgG4
19.260.000.001.840.381.3
24.411.940.001.830.0017.9
38.404.661.960.850.389.6
41.810.000.000.250.001
51.900.000.001.340.002
68.003.143.560.930.003.4
72.006
81.540.000.000.640.262.3
92.500.002.490.930.152.1
101.20
111.2000.8801
  • NOTE: Levels of antibody, avidity, and isotype of serum antibodies from patients with anti-HER2 responses was determined as defined in Materials and Methods. Inadequate amounts of serum were available to fully characterize some samples.