Table 1.

KRAS, EGFR, and HER2 mutation in resected NSCLC

Country (n)KRASEGFRHER2
Mutation (%)Mutation (%)Mutation (%)Gender (n)Mutation (%)Smoking (n)Mutation (%)Histology * (n)Mutation (%)
Japan (269)17 (6)70 (26)8 (3.0)Male (193)2 (1.0)NS (77)5 (6.5)Adeno. (157)8 (5.1)
Female (76)6 (7.9)S (192)3 (1.6)Others (112)0
Taiwan (145)5 (3)52 (36)2 (1.4)Male (71)1 (1.4)NS (106)2 (1.8)Adeno. (94)2 (2.1)
Female (74)1 (1.4)S (39)0Others (51)0
United States (157)19 (12)15 (10)0Male (85)0NS (40)0Adeno. (97)0
Female (72)0S (117)0Others (60)0
Australia (100)13 (13)12 (12)1 (1.0)Male (64)1 (1.6)NS (25)1 (4.0)Adeno. (46)1 (2.2)
Female (36)0S (75)0Others (54)0
Total (671)54 (8)149 (22)11 (1.6)Male (413)4 (1.0)NS (248)8 (3.2)Adeno. (394)11 (2.8)
Female (258)7 (2.7)S (423)3 (0.7)Others (277)0
  • Abbreviations: NS, never-smoker; S, smoker; Adeno., adenocarcinoma.

  • * Others include squamous cell, adenosquamous cell, and large cell carcinoma.