Table 1.

CHI3L1/YKL-40-associated genes

GeneFold change
CellsTumors
Ovalbumin72.81.5
Nicotinamide N-methyltransferase11.34.1
Collagen, type VI, α14.71.7
Collagen, type VI, α24.72.8
Tenascin C (hexabrachion)3.92.4
Basic helix-loop-helix domain containing, class B, 22.41.7
Epithelial membrane protein 12.41.6
Insulin-like growth factor binding protein 52.32.2
Collagen, type XVI, α12.12.2
Likely orthologue of rat brain specific binding protein/Ras-induced senescence 11.92.1
Transforming growth factor-β receptor II1.81.6
Vascular endothelial growth factor1.92.6
Transforming growth factor β-induced1.82.5
A kinase (PRKA) anchor protein 111.71.9
Cadherin 11, type 2, OB-cadherin (osteoblast)1.71.8
Pre-B-cell colony-enhancing factor1.74.5
ADP-ribosylation factor-like 71.61.7
KIAA0062 protein1.61.7
Caldesmon 11.51.8
Plasminogen activator inhibitor type 11.52.6
Paternally expressed 100.50.4
  • NOTE: In vivo and in vitro expression patterns for cells overexpressing CHI3L1/YKL-40 were compared. In vivo expression patterns were derived from glioblastoma tumor samples that were divided into two groups based on CHI3L1/YKL-40 expression levels, whereas in vitro profiles were obtained with CHI3L1/YKL-40 and mock-transfected cells. Genes that differed by 1.5-fold in these comparisons and were common to both in vitro and in vivo profiles are shown.