Table 2.

Cox univariate analysis of breast cancer samples with continuous variables (20-year survival) converted to ordinal categories using X-tile optimal cutpoints

MarkerNo. samples *Hazard ratio (95% confidence interval)P
β-catenin
    High82
    Low1172.663 (1.689-4.198)<0.0001
    Middle2521.702 (1.103-2.626)0.0162
ER (low)409 (118, 291) 1.624 (1.206-2.185)0.0014
HER2 (high)518 (454, 54)1.526 (1.036-2.249)0.0325
Ki-67 (high)434 (71, 363)1.623 (1.077-2.446)0.0206
PR (low)412 (198, 214)1.463 (1.113-1.923)0.0063
  • * Includes only those samples both with follow-up information and measurements for a particular marker.

  • The parenthesis contain first the number of samples in the “low” group followed by the number of samples in the “high” group (i.e., n = low, n = high).