Table 1.

Clinical characteristics of patients for ACF study

Patient groupAgeMale/femaleFamily history of colon cancer (%)History of adenomas or carcinomas (%)NSAID use (%)Smoking (pack-years)No. patients
Total64.20.94/13153521973
Patients with hyperproliferative ACF *69 ± 2.00.7/131645217.234
Patients without hyperproliferative ACF 60 ± 1.61.2/130435220.639
P <0.010.310.950.110.990.78
  • * Patients with large hyperproliferative ACF (PCNA transcript abundance or protein ≥2-fold of adjacent mucosa).

  • Patients without hyperproliferative ACF (patients with no ACF or small or nonhyperproliferative ACF).

  • Comparing patients with hyperproliferative ACF with those without hyperproliferative ACF.