Table 1.

IFN-γ production by chNKG2D-modified human T cells

IFN-γ (pg/mL)
Tumor cellsVectorwtNKG2DchNKG2DNo T cells
NDNDND
P815NDNDNDND
P815/MICANDND230 ± 19ND
RPMI88661,062 ± 84 *393 ± 2713,942 ± 1,543ND
K562111 ± 14ND3,964 ± 347ND
JurkatNDND217 ± 23ND
T47DNDND252 ± 8ND
MCF-7NDND987 ± 181ND
Panc-1NDND1,906 ± 122ND
DU145NDND1,766 ± 122ND
A375NDND520 ± 39ND
PC-3NDND1,504 ± 31ND
  • Abbreviation: ND, not detectable (<37 pg/mL).

  • * A representative result (mean ± SD of triplicates) of two or three independent experiments.