Variable | Case patients, n (%) | Control subjects, n (%) | OR (95% CI)
* or P^{†} | |||
---|---|---|---|---|---|---|

Micronuclei | ||||||

Pearson's χ^{2} test | ||||||

Spontaneous | ||||||

0 or 1 | 13 (9.4) | 52 (40.0) | ||||

2 or 3 | 61 (43.9) | 63 (48.5) | ||||

≥4 | 65 (46.8) | 15 (11.5) | <0.001 | |||

NNK induced | ||||||

1 or 2 | 5 (3.6) | 64 (49.2) | ||||

3 or 4 | 78 (56.1) | 58 (44.6) | ||||

≥5 | 56 (40.3) | 8 (6.2) | <0.001 | |||

Multivariate logistic | ||||||

Regression analysis | ||||||

Spontaneous | 139 | 130 | 2.06 (1.60-2.65) | |||

NNK induced | 139 | 130 | 2.32 (2.32-4.80) | |||

Nucleoplasmic bridges | ||||||

Pearson's χ^{2} test | ||||||

Spontaneous | ||||||

0 or 1 | 0 (0.0) | 112 (86.2) | ||||

2 or 3 | 48 (34.5) | 18 (13.9) | ||||

≥4 | 91 (65.5) | 0 (0.0) | <0.001 | |||

NNK induced | ||||||

0 or 2 | 0 (0.0) | 84 (64.6) | ||||

3 or 5 | 15 (10.8) | 46 (35.4) | ||||

≥6 | 124 (89.2) | 0 (0.0) | <0.001 | |||

Multivariate logistic | ||||||

Regression analysis | ||||||

Spontaneous | 139 | 130 | 29.05 (7.48-112.80) | |||

NNK induced | 139 | 130 | 45.52 (4.48-422.17) | |||

Nuclear buds | ||||||

Pearson's χ^{2} test | ||||||

Spontaneous | ||||||

0 | 102 (73.4) | 122 (95.3) | ||||

1 | 35 (25.2) | 6 (4.7) | ||||

2 | 2 (1.4) | 0 (0.0) | <0.001 | |||

NNK induced | ||||||

0 | 48 (34.5) | 113 (86.9) | ||||

1 | 59 (42.5) | 15 (11.5) | ||||

≥2 | 32 (23.0) | 2 (1.5) | 0.001 | |||

Multivariate logistic | ||||||

Regression analysis | ||||||

Spontaneous | 139 | 130 | 6.53 (2.37-18.01) | |||

NNK induced | 139 | 130 | 10.10 (4.67-21.87) |