Table 1.

Comparison of intestinal tumor frequency between ApcMin/+ and Rag−/−ApcMin/+ mice

GroupHh statusNo. miceTumor multiplicity (mean ± SE)
Small intestineLarge intestine
ApcMin/+937.89 ± 3.57a, e0.5 ± 0.3d
+1167.73 ± 11.36a, c2.5 ± 0.2d
Rag−/−ApcMin/+1682.69 ± 4.38b, e1.4 ± 0.3
+15104.7 ± 9.50b, c2.7 ± 0.6
  • NOTE: Data sharing a superscript letter are significantly different from each other. a, b, and c, P < 0.05; d, P < 0.01; e, P < 0.001. Mice were either uninfected or dosed with H. hepaticus (Hh) and tumor multiplicity in small and large intestine was quantitated as described in Materials and Methods. Total tumor numbers in small and large intestine were separately analyzed between groups by using unpaired t test with Welch's correction using Prism 4.0 software as described in Materials and Methods.