Table 2.

Differentially expressed genes with biological function between high- and low-risk patients

RankScoreGene nameSymbolUniGeneLocationGene ontology functionAgilent
227.734Keratin 14KRT14Hs.35521417q12-q21Cytoskeleton structureNo
718.387Inhibin, βAINHBAHs.287927p15-p13Receptor bindingYes
1616.081Microtubule actin cross-linking fact 1MACF1Hs.4724751p32-p31Microtubule bindingYes
1715.874Subfamily BCYP1B1Hs.1546542p21Electron transportYes
2614.543Protease, serine, 23PRSS23Hs.2533811q14.1Chymotrypsin activityNo
3014.303Transforming growth factor β inducedTGFBIHs.3693975q31Protein bindingNo
3114.292Influenza virus NS1A binding proteinIVNS1ABPHs.4971831q25.1-q31.1RNA processingNo
3314.180Tax1-binding protein 3TAX1BP3Hs.1295617p13Protein bindingYes
3513.364ATPase, Ca2+ transportingATP2A2Hs.50675912q23-q24.1ATP and cation bindingYes
3912.849Matrix metallopeptidase 2MMP-2Hs.51361716q13-q21Gelatinase A activityYes
4012.832StratifinSFNHs.5237181p36.11Protein kinase C inhibitor activityNo
4312.382Transcription elongation fact A-like 4TCEAL4Hs.194329Xq22.2Translation elongationNo
4611.949Protein 1BASP1Hs.2016415p15.1-p14Cytoskeleton structureNo
5011.654Annexin A5ANXA5Hs.4806534q26-q32Calcium ion bindingYes
5311.463Tumor protein p53-binding protein, 1TP53BP1Hs.44096815q15-q21Transcriptional activatorYes
5411.291Plectin 1PLEC1Hs.4342488q24Cytoskeleton structureNo
5511.272Actinin, α1ACTN1Hs.50976514q24.1-2Cytoskeleton structureYes
5611.131Zinc finger protein 537ZNF537Hs.27843619q12Transcription factor activityno
5711.113Lysine hydroxylasePLOD2Hs.4778663q23-q24Oxidoreducase activityYes
5810.830Galectin 1LGALS1Hs.44535122q13.1Signaling transductionYes
619.815Lysyl oxidase-like 2LOXL2Hs.1164798p21.3-p21.2Electron transportYes
678.699Spermine oxidaseSMOXHs.43333720p13Oxidoreducase activityYes
698.227Plexin A1PLXNA1Hs.4323293q21.3Semaphorin receptor activityNo
717.760Casein kinase 1, ϵCSNK1EHs.47483322q13.1Serine/threonine kinaseYes
727.498Serine/threonine kinase 19STK19Hs.4851026p21.3Serine/threonine kinaseno
736.474Collagen, type V, α1COL5A1Hs.2102839q34.2-.3Extracellular matrix structureNo
4−22.387Immunoglobulin κ constantIGKCHs.4496212p12Antigen bindingYes
8−18.200B-factor, properdinBFHs.697716p21.3Peptidase activityYes
9−17.775Cytochrome c oxidase subunit VibCOX6B2Hs.55054419q13.42Electron transportNo
12−16.895Spleen tyrosine kinaseSYKHs.3717209q22Tyrosine kinase activityYes
14−16.142Solute carrier family 35, E2SLC35E2Hs.5516121p36.33Catalytic activityNo
15−16.091Kynurenine aminotransferase IIIKAT3Hs.4818981p22.2Nucleic acid bindingYes
20−15.426PHD finger protein 8PHF8Hs.133352Xp11.22DNA bindingNo
36−13.234NADP+, solubleIDH1Hs.112232q33.3Oxidoreducase activityYes
37−13.089MHC complex, class II, DP β1HLA-DPB1Hs.4851306p21.3Protein bindingYes
44−12.168Ubiquitin protein ligase 1WWP1Hs.5334408q21Ubiquitin-protein ligaseNo
48−11.877ATP synthase, H+ transportingATP5G3Hs.4292q31.1Transporter activityYes
59−10.498Mitochondrial carrier homologue 1MTCH1Hs.4852626pter-p24.1Protein bindingNo
64−9.491Vaccinia-related kinase 1VRK1Hs.42266214q32Serine/threonine kinaseYes
66−9.234H3 histone, family 3AH3F3AHs.5336241q41/2q31.1Nuclear proteinNo
68−8.560Transcription factor 3TCF3Hs.37128219p13.3Transcription factor activityYes
74−6.306Nucleoporin 54 kDaNUP54Hs.4304354q21.1TransportYes