Table 1.

Identified sequence variants in the NKX3.1 gene

Variant IDPositionAmino acid changeMinor alleleFrequency
−507AGnPromoterAG60.474
−360G/APromoterA0.2
−276 18-bp INDELPromoterdel0.167
−46G/T5′-UTRT0.005
−15A/G5′-UTRG0.185
49G/ACodingA17TA0.005
154C/TCodingR52CT0.05
1454A/GCodingT164AG0.003
1495T/CCodingC0.01
1558G/ACodingP198PA0.003
1870T/C3′-UTRT0.308
1977T/C3′-UTRT0.141
2179AGn3′-UTRAG30.495
2395G/A3′-UTRA0.46
2553T/C3′-UTRC0.011
2815C/A3′-UTRA0.008
3318G/T3′-UTRT0.007
3597G/C3′-UTRC0.003
3992C/G3′-UTRG0.004
4071A/G3′-UTRG0.004
4237T/C3′-UTRC0.007