Table 1.

Summary of TMPRSS2/ERG fusion types

TypesTMPERGSizeDescription of TMP:ERG fusionn (%)
I12-7138-762779Exon 1 of TMP + beginning of ERG exon 27 (20)
II12-71140-762678Exon 1 of TMP + beginning of ERG exon 34 (11)
III12-71226-762591Exon 1 of TMP + beginning of ERG exon 430 (86)
IV12-71444-762373Exon 1 of TMP + beginning of ERG exon 51 (3)
V12-14238-762850Exons 1 and 2 of TMP + beginning of ERG exon 23 (9)
VI12-142226-762662Exons 1 and 2 of TMP + beginning of ERG exon 49 (26)
VII12-142444-762444Exons 1 and 2 of TMP + beginning of ERG exon 52 (6)
VIII12-365226-762885Exons 1-3 of TMP + beginning of ERG exon 42 (6)
  • NOTE: Fusion sites, locations within each gene, lengths of fusion PCR products (in bp), and number and percentage of cancers expressing each type of fusion. Base pair numbers are based on Genbank accession nos. NM_005656 (TMPRSS2) and NM_004449 (ERG). Percent is expressed as the percentage with that isoform of all cancers expressing any fusion mRNA.