Table 1.

The frequency of promoter polymorphism of hDB-1 in prostate cancer patients and normal control

PositionRFLPAlleleFrequency in patientsFrequency in control
No.Relative (%)No.Relative (%)
5′-UTR (−20 G/A)ScrFI12016.11222.2
1+26048.42851.9
24435.51425.9
5′-UTR (−44 C/G)HgaI18064.54175.9
1+24133.11222.2
232.411.9
5′-UTR (−52 G/A)NlaIV12419.4814.8
1+25241.92546.3
24838.72138.9
5′-UTR (−688 G/C)Cac8I16653.23259.3
1+25141.12037
297.123.7
  • NOTE: Allele 1 designates the absence of polymorphism; allele 2, the homozygotes for the polymorphisms; and allele 1+2, the heterozygotes for both alleles 1 and 2. Allele frequencies are given as absolute numbers and relative frequencies in a total of 124 patients and 54 controls.