Table 1.

Genomic mutations in melanoma cell lines

Cell lineBRAF * (exons 11 and 15)CRAF * (exon 7)K-RAS * (exons 2 and 3)N-RAS * (exons 2 and 3)MC1R *
Sbcl2WTWTWTQ61KV60L
WM852WTWTWTQ61RR160W
WM1361WTWTWTQ61KV60L
WM1366WTWTWTQ61LV60L/R160W/W169stop
WM1791cWTWTT50I/Q61HWTWT
SKMel2WTWTQ61RWTR142H
A375V600EWTWTWTR151C
Colo829V600EWTWTWTV92M
SkMel28V600EWTWTWTS83P/I155T
WM266.4V600DWTWTWTR160W
  • * Wild-type.

  • Heterozygote.