Table 2.

GO enrichment analysis of differentially expressed genes

G1 vs G2aG2a vs G2bG2b vs G3
P *T E O §PTEOPTEO
Biological process
    Cell cycle6.2E−068530.7675.7E−288537.08502.5E−068532.2912
    Chromatin packaging and remodeling1.3E−021960.1822.5E−021961.635
    Mitosis2.7E−022870.2626.8E−152872.38221.1E−032870.775
    Inhibition of apoptosis4.4E−031271.0554.9E−031270.343
    Oncogenesis1.6E−026000.5435.5E−046004.98145.5E−036001.616
    Cell motility3.6E−022912.4264.4E−022910.783
    Stress response5.0E−031871.556
Molecular function
    Kinase activator1.1E−03540.0527.2E−06540.456
    Histone3.5E−03990.0925.0E−02990.823
    Nucleic acid binding1.3E−0230142.77
    Microtubule family cytoskeletal protein7.6E−072331.93124.2E−042330.635
    Chemokine7.5E−03480.132
    Nonreceptor serine/threonine protein kinase7.8E−042892.49
    Extracellular matrix linker protein1.9E−02250.212
Pathway
    Insulin/IGF pathway-MAPKK/MAPK cascade4.9E−02560.051
    Apoptosis signaling pathway4.9E−021310.352
    Ubiquitin proteasome pathway3.0E−02800.663
  • Abbreviations: IGF, insulin-like growth factor; MAPKK, mitogen-activated protein kinase kinase.

  • * P value for significance of GO term enrichment.

  • Total number of genes with given GO annotation.

  • Expected number of genes with given GO annotation.

  • § Observed number of genes with given GO annotation.