Table 2.

High-priority glioblastoma subtype-unique MCRs

Cytogenetic bandLocus (Mb)Minimal common regionMCR recurrenceViral integration sitesMicroRNACandidate genes
Position (Mb)Size (Mb)Peak valueTranscriptsGain/lossAmp/del
T%T%
Primary glioblastoma
1p32.3-1p32.351.13-52.2151.13-52.211.081.031239.113.0EPS15
2q33.1-2q33.2201.36-203.68201.6-201.920.320.955412.139.1
6p21.2-6p21.237.71-39.1137.71-39.111.390.85539.113.0
7p14.1-7p14.138.04-38.238.04-38.20.151.16232987.9412.1
7p12.3-7p12.149.72-50.8650.28-50.860.574.2742781.8618.2
7q22.1-7q22.1100.03-100.14100.03-100.140.100.8762781.826.1
9q33.2-9q33.3122.66-122.97122.66-122.970.311.06826.113.0
19q13.33-19q13.3353.8-53.9653.8-53.960.150.84131236.413.0
1p36.11-1p35.327.62-28.6527.62-28.651.02−0.621639.113.0
1q42.2-1q42.3230.11-231.05230.11-231.050.94−1.025412.126.1
4q33-4q34.1171.01-175.63171.01-175.634.61−0.671526.126.1
6p21.32-6p21.3232.47-32.7232.47-32.720.25−0.81739.126.1
6p12.1-6p12.153.89-55.7353.89-55.731.83−0.639515.226.1
6q21-6q21109.41-109.88109.41-109.880.46−0.6381236.4721.2
6q25.3-6q25.3158.06-160.18158.06-160.082.01−0.70171545.51030.3NKI-34
9p13.3-9p13.235.04-38.5435.72-35.90.17−0.7281030.339.1
9q21.11-9q21.269.23-77.2769.23-77.278.02−0.672939.139.1Anxa1hsa-mir-204
10q11.23-10q22.151.26-71.8669.66-70.640.98−0.80153193.91957.6
11q13.5-11q14.177.26-78.0577.26-78.050.78−0.809515.226.1
17q21.31-17q21.3340.54-46.344.04-44.30.25−0.927412.139.1hsa-mir-196a-1
21p11.2-21q22.119.93-31.1114.4-15.260.85−0.697515.226.1
Secondary glioblastoma
1q42.13-1q44224.91-245.43231.04-234.333.271.622229.529.5D8Ertd233e
3p24.1-3p21.3229.91-44.4329.91-44.4314.510.949629.514.8CKLFSF728b, hsa-mir-26a-1, hsa-MLH1.CTNNB1
8q23.1-8q24.3109.86-146.26144.87-146.261.381.7655733.3523.8RECQL4
10p15.3-10p11.210.28-35.9730.64-35.975.330.8418523.8314.3MAP3K8
11q13.5-11q14.177.26-78.0577.26-78.050.783.40929.514.8
12p13.33-12p13.20.17-12.153.81-6.682.862.4538628.6628.6CCND2ZNF384
12p12.3-12q1215.02-37.9821.59-29.567.962.5637628.6523.8KRAS2.LRMP, STK381, BHLHb3KRAS2
12q13.13-12q13.1352-52.1652-52.160.154.55529.514.8
12q14.2-12q14.262.87-63.462.87-63.40.521.926314.314.8
12q21.1-12q21.273.73-74.7173.73-74.710.981.13629.514.8
12q24.33-12q24.33130.94-131.08130.94-131.080.121.26329.514.8
18q11.2-18q11.217.33-20.917.33-20.93.560.812129.529.5Evi3hsa-mir-133a-1, hsa-mir-1-2
18q12.1-18q12.326.82-39.1126.82-39.1112.270.824429.529.5MAPRE2hsa-mir-187
19q12-19q13.234.79-43.4935.73-38.963.220.8623419.029.5CEBPA
1p13.3-1p13.3107.82-108.96107.82-108.961.13−0.998314.314.8
2q36.1-2q36.1223.26-224.57223.26-224.571.30−0.767314.329.5
3p24.3-3p24.319.55-2019.55-200.44−1.644523.8314.3
5q23.1-5q33.3118.2-156.28134.21-140.596.37−0.67104523.8523.8KLH-L3
6q14.1-6q1579.7-88.0679.7-88.068.34−0.7630838.1838.1A930014C21Rik
6q23.3-6q23.3136.59-138.25136.59-138.251.65−0.76111152.41047.6
9p21.2-9p21.227.51-27.9427.51-27.940.42−0.864838.1419.0
10p15.3-10p130-28-12.910.28-3.823.53−0.62151152.4628.6COPEB
11q23.2-11q25113.77-133.78127.83-133.785.93−0.6934628.6419.0Fli1|Ets1FLI1
12q14.1-12q14.157.55-58.4757.55-58.470.91−0.76229.529.5
12q14.2-12q1563.17-67.4563.39-67.454.05−0.6527628.6314.3RAP1BHMGA2
12q24.33-12q24.33129.17-129.39129.17-129.390.21−0.642314.329.5
12q24.33-12q24.33131.09-132.35131.09-132.351.25−0.6419419.029.5
14q13.1-14q13.233.97-34.9533.97-34.950.97−0.6213419.029.5NFKBIA
14q32.12-14q32.3190.79-101.4790.79-101.4710.67−0.67100733.3523.8Evi151hsa-370, hsa-mir-299, hsa-mir-299TRIP11, GOLGA5, TCL1A, BCL11B
14q32.32-14q32.33102.03-106.34102.03-106.344.29−0.67233628.6419.0IGH4, AKT1hsa-mir-203
16q23.1-16q23.273.98-79.1573.98-79.155.16−0.7118419.0314.3MAF
18q12.3-18q21.3130.57-54.2240.89-50.129.21−0.7343523.8419.0Evi153
20p13-20p11.210.02-25.617.9-18.7210.81−0.8561314.3314.3SNX5
20p13-20p11.210.02-25.6119.96-24.64.63−0.73 44314.3314.3