Table 1.

Relative expression of E-cadherin and ZEB-1 in NSCLC cell lines

Cell lineGefitinib (IC50)E-CadherinZEB1
RT-PCRMicroarrayRT-PCRMicroarray
Sensitive
    H32250.01513,9267,0189.4E-025.9
    H3580.1810,4534,7015.027.4
    H3220.256,6425,8613.057.0
    Calu30.34,3595,5326.987.8
    H16480.386,6422,8251.297.6
    HCC780.61,2143,673177.0
Intermediate
    H212617093,9469.47.2
    HCC9531371,5770.56.8
    H441492592613.68
    HCC19340.063,1491537.6
    Colo6994.29.8E-0658.97.5
    H21225.98401,671297.9
    A5498.21321,50838830.3
    HCC448.40.5616219.8
    H12998.61.0E-04513046.1
    H20099.85586,9592.66.5
Resistant
    HCC1510171869921.3
    H1703122.1E-025.412335.6
    H15712.81.98E-04535640.5
    H126412.93.4E-05516648.0
    H46012.91.4E-01517960.7
    H52013.6588433710.1
r−0.78−0.760.760.75
P<0.001<0.001<0.001<0.001