Table 3.

Adjusted ORs for EGFR and K-RAS mutations

EGFRK-RAS
Mu/WOR (95% CI)PMu/WOR (95% CI)P
Methylation status
    p16INK4a
        U72/611.00 (reference)0.0018/1251.00 (reference)0.007
        M2/290.07 (0.02-0.33)8/234.93 (1.54-15.7)
    RASSF1A
        U55/561.00 (reference)0.4889/1021.00 (reference)0.56
        M19/340.76 (0.36-1.63)7/461.39 (0.46-4.19)
    APC
        U45/501.00 (reference)0.6099/861.00 (reference)0.8
        M29/401.21 (0.59-2.48)7/620.87 (0.29-2.59)
    RARβ
        U45/591.00 (reference)0.9419/951.00 (reference)0.474
    M29/310.97 (0.47-2.01)7/531.50 (0.50-4.53)
    CDH13
        U61/551.00 (reference)0.0099/1071.00 (reference)0.302
        M13/350.34 (0.15-0.77)7/411.78 (0.59-5.36)
Methylation index, 1-unit increase0.70 (0.52-0.95)0.0231.46 (0.95-2.25)0.086
  • NOTE: M, methylated; U, unmethylated.