Table 1.

Effects of soy phytochemicals on tumor cell apoptosis and proliferation, tumor angiogenesis, and blood levels of IGF-I, IGFBP-3, and bFGF

TreatmentApoptosis index (%)Proliferation index (%)MVD (vessels/field)IGF-I (ng/mL)IGFBP-3 (ng/mL)bFGF (ng/mL)
Control (16)5.1 ± 1.0a57.4 ± 6.3a2.6 ± 0.5a16.5 ± 0.7a1,285.6 ± 423.6a46.9 ± 6.6a
SPC (16)18.5 ± 4.1b48.7 ± 2.5a1.7 ± 0.6b5.4 ± 2.1bc1,365.7 ± 321.1a60.9 ± 11.2a
Genistin (16)18.6 ± 3.5b44.8 ± 5.1a1.3 ± 0.2b10.0 ± 3.8ac1,245.1 ± 216.2a39.9 ± 4.7a
  • NOTE: Values are means ± SE. Within a column, means not sharing a common superscript letter are significantly different (P < 0.05). See text for P values for specific comparisons.