Table 2.

Summary of immunohistochemical data

TissueEP4 receptor status
+/−+++
Normal colon910
Colon adenoma1453
Colon adenocarcinoma007
Colon ulcerative colitis241
  • NOTE: Immunohistochemical localization of EP4 receptor protein expression in normal colon, ulcerative colitis, colorectal adenoma, and colorectal adenocarcinoma. Scoring was −/+ (negative to weakly positive), + (moderately positive), ++ (strongly positive).