Table 1.

Details of cases studied and abnormalities found through mutation screening

SampleDiagnosisSexAge (y)Treatment before sample removalSample usedSomatic mutations in this studyC:G>TA transitionsC:G>T:A transitions at CpGMSH6 mutation
PD1487a/Gli 56 TGlioblastomaM54Radiotherapy, chemotherapyRecurrence34340Het C1453T, Q485X; Het G3907A, A1303T
PD1489a/Gli 60 TGlioblastomaM47Radiotherapy, chemotherapyRecurrence30292Hom delG2425, V809X
PD1493a/Gli 70 TAnaplastic oligodendroglioma (grade 3)F48NonePrimary111Absent
PD1494a/Gli 72 TAnaplastic oligoastrocytoma (grade 3)F50NonePrimary000Absent
PD1536a/xT-155 TDGlioblastomaM51RadiotherapyRecurrence000Absent
PD1537a/xT-924 TDGlioblastomaM71NonePrimary000Absent
PD1538a/xT-2560 TDGlioblastomaM71NonePrimary000Absent
PD1540a/xT-3058 TDGlioblastomaF69NonePrimary000Absent
D542MGGlioblastomaF45Not knownNot known000Absent