Table 2.

Sequence context of C:G>T:A mutations observed in PD1487a and PD1489a compared with the expected sequence context

Sequence context of mutationACACCAGCATCAACCCCCGCCTCCACGCCGGCGTCGACTCCTGCTTCT
Percent observed mutations (%)0856112231402029837
Percent expected mutations (%)71078677824335888
  • NOTE: The expected sequence context was derived from the entire set of trinucleotides centered around all cytosines in the coding sequences of the protein kinases. Underlined C is the mutated base.