Table 1.

Loci of high-level amplification (log 2 ratio > 2.5) detected in NSCLC cell lines by array-CGH analysis using MCG Whole Genome Array-4500

No.BACLocus *Cell line (total 20)Possible candidate gene No. known genes
Chromosome bandPositionnName
1RP11-81F242p24.3chr2:15,177,504-15,178,2171VMRC-LCDMYCN3
RP11-451A142p24.3chr2:15,927,694-15,928,2091VMRC-LCDMYCN
2RP11-542D132q11.2chr2:97,564,600-97,795,0251VMRC-LCD16
3RP11-62G135q34chr5:160,654,723-160,806,0431VMRC-LCD4
4RP11-237F248q24.21chr8:128,822,387-128,822,8272ABC-1MYC1
RP11-89L168q24.21chr8:129,633,607-129,784,9542ABC-1, NCI-H460MYC
  • * Based on UCSC Genome Browser, May 2004 Assembly.

  • Representative candidate oncogene located around BAC.